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PONS

PONS: Patient-Derived Neurons as a Novel Test System for Schizophrenia Drug Development

Induced pluripotent stem cells from fibroblasts of schizophrenic and autistic patients will be differentiated in neurons. This novel in vitro system will be analyzed upon compound action at transcriptome, proteome and histological level and matched with cultured rodent derived neurons.
Acronym: 
PONS
Project ID: 
7 675
Ranking: 
21
Cut-off: 
9
Start date: 
01-06-2013
Project Duration: 
39months
Project costs: 
2 339 670.00€
Technological Area: 
Biology / Biotechnology
Market Area: 
Genomics / Proteomics / Metabolomics