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DERMAL

A novel topical therapy for Atopic Dermatitis through development of LXR agonists

This project will deliver a novel topical therapy for Atopic Dermatitis (AD). AD is a common, chronic, inflammatory skin disease. A great body of evidence supports Liver X Receptors (LXRs) as a therapeutic target for AD. The DERMAL project will perform lead selection and preclinical development based on a newly identified chemical series of LXR agonists. This project will produce formulated lead compounds that will be ready for clinical trials within 18 months after completion of this project.
Acronym: 
DERMAL
Project ID: 
10 449
Ranking: 
8
Cut-off: 
5
Start date: 
01-10-2016
Project Duration: 
36months
Project costs: 
3 439 180.00€
Technological Area: 
Pharmaceutical Products / Drugs
Market Area: 
Drug delivery and other equipment (including kidney dialysis machines)